Version 5.4
Mus musculus Protein: Atp6v1g2
Summary
InnateDB Protein IDBP-177453.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp6v1g2
Protein Name ATPase, H+ transporting, lysosomal V1 subunit G2
Synonyms 1500002D01Rik; Atp6g2; NG38; VAG2;
Species Mus musculus
Ensembl Protein ENSMUSP00000069482
InnateDB Gene IDBG-177451 (Atp6v1g2)
Protein Structure
UniProt Annotation
Function Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subcellular Localization Melanosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0015992 proton transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0016471 vacuolar proton-transporting V-type ATPase complex
GO:0030285 integral component of synaptic vesicle membrane
GO:0042470 melanosome
Protein Structure and Domains
PDB ID MGI:1913487
InterPro IPR005124 Vacuolar (H+)-ATPase G subunit
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WTT4
PhosphoSite PhosphoSite-Q9WTT4
TrEMBL Q54A87
UniProt Splice Variant
Entrez Gene 66237
UniGene Mm.476618
RefSeq NP_075668
MGI ID
MGI Symbol Atp6v1g2
OMIM
CCDS CCDS37597
HPRD
IMGT
EMBL AB076405 AC007080 AK011945 BC020190 BC062380 CH466666 CR974444
GenPept AAD30176 AAH20190 AAH62380 BAB27931 BAC10288 EDL26625

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca