Version 5.4
Mus musculus Protein: Sp5
Summary
InnateDB Protein IDBP-177812.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sp5
Protein Name trans-acting transcription factor 5
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000097620
InnateDB Gene IDBG-177810 (Sp5)
Protein Structure
UniProt Annotation
Function Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0036342 post-anal tail morphogenesis
GO:0060349 bone morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1927715
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JHX2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 64406
UniGene Mm.423397
RefSeq NP_071880
MGI ID
MGI Symbol Sp5
OMIM
CCDS CCDS16106
HPRD
IMGT
EMBL AF279479 AK036234 BC116691 BC117505
GenPept AAF87798 AAI16692 AAI17506 BAC29355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca