Version 5.4
Mus musculus Protein: Gorasp2
Summary
InnateDB Protein IDBP-178019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gorasp2
Protein Name golgi reassembly stacking protein 2
Synonyms 0610011A07Rik; 2410043M02Rik; 5730520M13Rik; 9430094F20Rik; AW552058; GOLPH2; GRASP55; GRS2; p59;
Species Mus musculus
Ensembl Protein ENSMUSP00000028509
InnateDB Gene IDBG-178017 (Gorasp2)
Protein Structure
UniProt Annotation
Function Plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. {ECO:0000269PubMed:10487747}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:10487747}; Lipid-anchor {ECO:0000269PubMed:10487747}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006996 organelle organization
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2135962
InterPro IPR001478 PDZ domain
IPR024958 GRASP55/65 PDZ-like domain
PFAM PF00595
PF13180
PF04495
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99JX3
PhosphoSite PhosphoSite-Q99JX3
TrEMBL
UniProt Splice Variant
Entrez Gene 70231
UniGene Mm.470827
RefSeq NP_081628
MGI ID
MGI Symbol Gorasp2
OMIM
CCDS CCDS16109
HPRD
IMGT
EMBL AK033413 AK077683 AK077706 AK148337 AK151843 AK152475 AK152544 AK152603 AK153049 AK169382 BC005600 BC016455
GenPept AAH05600 AAH16455 BAC28276 BAC36954 BAC36969 BAE28492 BAE30735 BAE31249 BAE31299 BAE31351 BAE31677 BAE41129

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca