Version 5.4
| Mus musculus Protein: Sag | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-178790.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Sag | ||||||||
| Protein Name | retinal S-antigen | ||||||||
| Synonyms | A930001K18Rik; Arr1; arrestin; Irbp; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000076948 | ||||||||
| InnateDB Gene | IDBG-178788 (Sag) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated- phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | Note=S-antigen induces autoimmune uveitis. | ||||||||
| Tissue Specificity | Retina and pineal gland. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:98227 | ||||||||
| InterPro |
IPR000698
Arrestin IPR011021 Arrestin-like, N-terminal IPR011022 Arrestin C-terminal-like domain IPR014756 Immunoglobulin E-set |
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| PFAM |
PF00339
PF02752 |
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| PRINTS |
PR00309
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| PIRSF | |||||||||
| SMART |
SM01017
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P20443 | ||||||||
| PhosphoSite | PhosphoSite-P20443 | ||||||||
| TrEMBL | Q8C8Y8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 20215 | ||||||||
| UniGene | Mm.1276 | ||||||||
| RefSeq | NP_033144 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Sag | ||||||||
| OMIM | |||||||||
| CCDS | CCDS35656 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK044214 AK143098 AK149299 BC016498 CH466520 M24086 | ||||||||
| GenPept | AAA40090 AAH16498 BAC31820 BAE25268 BAE28798 EDL40140 | ||||||||