InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cxcl2

Summary

InnateDB Protein

IDBP-178957.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cxcl2

Protein Name

chemokine (C-X-C motif) ligand 2

Synonyms

CINC-2a; Gro2; GROb; Mgsa-b; MIP-2; MIP-2a; Mip2; Scyb; Scyb2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000074885

InnateDB Gene

IDBG-178955 (Cxcl2)

Protein Structure

UniProt Annotation

Function

Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	4 [view]
Protein-DNA	8 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008009	chemokine activity

Biological Process

GO:0001975	response to amphetamine
GO:0002237	response to molecule of bacterial origin
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0009408	response to heat
GO:0010332	response to gamma radiation
GO:0030593	neutrophil chemotaxis
GO:0030595	leukocyte chemotaxis
GO:0032355	response to estradiol
GO:0042060	wound healing
GO:0045087	innate immune response (InnateDB)
GO:0051384	response to glucocorticoid
GO:0070997	neuron death
GO:0071222	cellular response to lipopolysaccharide
GO:0071347	cellular response to interleukin-1