Version 5.4
Mus musculus Protein: Ugt1a9
Summary
InnateDB Protein IDBP-179165.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ugt1a9
Protein Name UDP glucuronosyltransferase 1 family, polypeptide A9
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000073444
InnateDB Gene IDBG-488746 (Ugt1a9)
Protein Structure
UniProt Annotation
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Subcellular Localization Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in liver and at lower levels in stomach and kidney. {ECO:0000269PubMed:14672974}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015020 glucuronosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008152 metabolic process
GO:0030259 lipid glycosylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3576092
InterPro IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235 Glycosyl transferase, family 28, C-terminal
PFAM PF00201
PF04101
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q62452
PhosphoSite PhosphoSite-Q62452
TrEMBL
UniProt Splice Variant
Entrez Gene 394434
UniGene Mm.467021
RefSeq NP_964006
MGI ID
MGI Symbol Ugt1a9
OMIM
CCDS CCDS15138
HPRD
IMGT
EMBL AC087780 AC087801 AY227200 BC138699 BC146021 L27122
GenPept AAA40524 AAI38700 AAI46022 AAP48599

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca