InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gbx2

Summary

InnateDB Protein

IDBP-179811.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gbx2

Protein Name

gastrulation brain homeobox 2

Synonyms

D130058E05Rik; Gbx-2; MMoxA; Stra7;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048508

InnateDB Gene

IDBG-179809 (Gbx2)

Protein Structure

UniProt Annotation

Function

May act as a transcription factor for cell pluripotency and differentiation in the embryo.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in adult brain, spleen and female genital tract. No expression in heart, liver, lung, kidney, or testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001569	patterning of blood vessels
GO:0001755	neural crest cell migration
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007411	axon guidance
GO:0008283	cell proliferation
GO:0021549	cerebellum development
GO:0021555	midbrain-hindbrain boundary morphogenesis
GO:0021568	rhombomere 2 development
GO:0021794	thalamus development
GO:0021884	forebrain neuron development
GO:0021930	cerebellar granule cell precursor proliferation
GO:0030902	hindbrain development
GO:0030917	midbrain-hindbrain boundary development
GO:0035239	tube morphogenesis
GO:0042472	inner ear morphogenesis
GO:0048483	autonomic nervous system development