InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atrnl1

Summary

InnateDB Protein

IDBP-180044.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atrnl1

Protein Name

attractin like 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000076514

InnateDB Gene

IDBG-180042 (Atrnl1)

Protein Structure

UniProt Annotation

Function

May play a role in melanocortin signaling pathways that regulate energy homeostasis. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Highly expressed in brain, heart, lung, kidney and liver. In the central nervous system, it is highly expressed in the dentate gyrus, CA1-3 regions of the hippocampus, and the ventral taenia tecta. {ECO:0000269PubMed:18064672}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007275	multicellular organismal development

Cellular Component

GO:0005575	cellular_component
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2147749

InterPro

IPR000742 Epidermal growth factor-like domain
IPR000859 CUB domain
IPR001304 C-type lectin
IPR002049 EGF-like, laminin
IPR002165 Plexin
IPR006652 Kelch repeat type 1
IPR013111 EGF-like domain, extracellular
IPR016187 C-type lectin fold
IPR016201 Plexin-like fold

PFAM