InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ckap4

Summary

InnateDB Protein

IDBP-180534.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ckap4

Protein Name

cytoskeleton-associated protein 4

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000050336

InnateDB Gene

IDBG-180532 (Ckap4)

Protein Structure

UniProt Annotation

Function

High-affinity epithelial cell surface receptor for APF. {ECO:0000250}.Mediates the anchoring of the endoplasmic reticulum to microtubules. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Translocates to the perinuclear region upon APF- stimulation. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0044822	poly(A) RNA binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005811	lipid particle
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome