InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sept11

Summary

InnateDB Protein

IDBP-180565.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sept11

Protein Name

septin 11

Synonyms

6230410I01Rik; AW548875; D5Ertd606e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000074293

InnateDB Gene

IDBG-180563 (Sept11)

Protein Structure

UniProt Annotation

Function

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). {ECO:0000250, ECO:0000305}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:17546647}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:17546647}. Cell junction, synapse {ECO:0000269PubMed:17546647}. Cell projection, dendritic spine {ECO:0000269PubMed:17546647}. Cell projection, axon {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0007049	cell cycle
GO:0051291	protein heterooligomerization
GO:0051301	cell division

Cellular Component

GO:0001725	stress fiber
GO:0030054	cell junction
GO:0030424	axon
GO:0031105	septin complex
GO:0043197	dendritic spine
GO:0045202	synapse
GO:0070062	extracellular vesicular exosome