InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Esm1

Summary

InnateDB Protein

IDBP-183559.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Esm1

Protein Name

endothelial cell-specific molecule 1

Synonyms

0610042H23Rik; AV004503; ESM-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040187

InnateDB Gene

IDBG-183557 (Esm1)

Protein Structure

UniProt Annotation

Function

Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005171	hepatocyte growth factor receptor binding
GO:0005178	integrin binding
GO:0005520	insulin-like growth factor binding

Biological Process

GO:0001525	angiogenesis
GO:0001558	regulation of cell growth
GO:0002040	sprouting angiogenesis
GO:0008284	positive regulation of cell proliferation
GO:1902204	positive regulation of hepatocyte growth factor receptor signaling pathway