Version 5.4
Mus musculus Protein: Mzt1
Summary
InnateDB Protein IDBP-183794.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mzt1
Protein Name mitotic spindle organizing protein 1
Synonyms 2410129H14Rik; AI120158; Mozart1;
Species Mus musculus
Ensembl Protein ENSMUSP00000037557
InnateDB Gene IDBG-183792 (Mzt1)
Protein Structure
UniProt Annotation
Function Required for gamma-tubulin complex recruitment to the centrosome. {ECO:0000269PubMed:20360068}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:20360068}. Cytoplasm, cytoskeleton, spindle {ECO:0000269PubMed:20360068}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0033566 gamma-tubulin complex localization
Cellular Component
GO:0005813 centrosome
GO:0005819 spindle
GO:0008274 gamma-tubulin ring complex
Protein Structure and Domains
PDB ID MGI:1924039
InterPro IPR022214 Protein of unknown function DUF3743
PFAM PF12554
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BUR9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 76789
UniGene Mm.490543
RefSeq NP_780454
MGI ID
MGI Symbol Mzt1
OMIM
CCDS CCDS49554
HPRD
IMGT
EMBL AK082817 AK150268 AK151232 AK151358 AK151819 AK160911 AK165605 AK168114 AK169036 AK170746 BC117005 BC117007
GenPept AAI17006 AAI17008 BAC38633 BAE29424 BAE30224 BAE30333 BAE30716 BAE36085 BAE38289 BAE40085 BAE40827 BAE41999

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca