InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bcl2l13

Summary

InnateDB Protein

IDBP-184025.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bcl2l13

Protein Name

BCL2-like 13 (apoptosis facilitator)

Synonyms

BCL-RAMBO; E430016C20Rik; Mil-1; Mil1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000009256

InnateDB Gene

IDBG-184023 (Bcl2l13)

Protein Structure

UniProt Annotation

Function

May promote the activation of caspase-3 and apoptosis.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006915	apoptotic process
GO:0042981	regulation of apoptotic process

Cellular Component

GO:0005739	mitochondrion
GO:0016021	integral component of membrane
GO:0031966	mitochondrial membrane

Protein Structure and Domains

PDB ID

MGI:2136959

InterPro

IPR002475 Bcl2-like
IPR026298 Blc2 family

PFAM

PF00452

PRINTS

PR01862

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P59017

PhosphoSite

PhosphoSite-P59017

TrEMBL

UniProt Splice Variant

Entrez Gene

94044

UniGene

Mm.408552

RefSeq

NP_705736

MGI ID

MGI Symbol

Bcl2l13

OMIM

CCDS

CCDS20485

HPRD

IMGT

EMBL

AK047223 AK132774 AK168833 BC027307 BC029016 CH466523

GenPept

AAH27307 AAH29016 BAC32999 BAE21351 BAE40657 EDK99647