Version 5.4
Mus musculus Protein: Commd6
Summary
InnateDB Protein IDBP-184348.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Commd6
Protein Name COMM domain containing 6
Synonyms 1110059J08Rik; 1700063H17Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000097912
InnateDB Gene IDBG-184346 (Commd6)
Protein Structure
UniProt Annotation
Function Inhibits TNF-induced NFKB1 activation. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051059 NF-kappaB binding
Biological Process
GO:0032088 negative regulation of NF-kappaB transcription factor activity
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1913450
InterPro IPR009886 HCaRG
PFAM PF07258
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3V4B5
PhosphoSite PhosphoSite-Q3V4B5
TrEMBL B7ZNP2
UniProt Splice Variant
Entrez Gene 66200
UniGene Mm.400267
RefSeq NP_001028304
MGI ID
MGI Symbol Commd6
OMIM
CCDS CCDS37000
HPRD
IMGT
EMBL AK004316 BC132261 BC132265 BC145360
GenPept AAI32262 AAI32266 AAI45361 BAE43169

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca