Version 5.4
Mus musculus Protein: Tmem27
Summary
InnateDB Protein IDBP-184490.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem27
Protein Name transmembrane protein 27
Synonyms 0610008J07Rik; NX-17; NX17;
Species Mus musculus
Ensembl Protein ENSMUSP00000015545
InnateDB Gene IDBG-184488 (Tmem27)
Protein Structure
UniProt Annotation
Function Regulator of SNARE complex function. Stimulator of beta cell replication. {ECO:0000269PubMed:16330323, ECO:0000269PubMed:16330324}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Kidney; collecting ducts. Pancreas; beta cells of islets. {ECO:0000269PubMed:11278314, ECO:0000269PubMed:16330323, ECO:0000269PubMed:16330324}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008241 peptidyl-dipeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0051957 positive regulation of amino acid transport
Cellular Component
GO:0016021 integral component of membrane
GO:0031526 brush border membrane
Protein Structure and Domains
PDB ID MGI:1926234
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ESG4
PhosphoSite PhosphoSite-Q9ESG4
TrEMBL
UniProt Splice Variant
Entrez Gene 57394
UniGene Mm.420896
RefSeq NP_065651
MGI ID
MGI Symbol Tmem27
OMIM
CCDS CCDS30517
HPRD
IMGT
EMBL AF178085 AK002337 AK148534 BC049912
GenPept AAG09306 AAH49912 BAB22022 BAE28605

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca