Version 5.4
Mus musculus Protein: Ppt1
Summary
InnateDB Protein IDBP-184543.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Ppt1
Protein Name palmitoyl-protein thioesterase 1
Synonyms 9530043G02Rik; AA960502; C77813; CLN1; D4Ertd184e; INCL; PPT;
Species Mus musculus
Ensembl Protein ENSMUSP00000095512
InnateDB Gene IDBG-184539 (Ppt1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008474 palmitoyl-(protein) hydrolase activity
Biological Process
GO:0002084 protein depalmitoylation
GO:0006309 apoptotic DNA fragmentation
GO:0006464 cellular protein modification process
GO:0006898 receptor-mediated endocytosis
GO:0006907 pinocytosis
GO:0007040 lysosome organization
GO:0007042 lysosomal lumen acidification
GO:0007269 neurotransmitter secretion
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007601 visual perception
GO:0007625 grooming behavior
GO:0008306 associative learning
GO:0008344 adult locomotory behavior
GO:0015031 protein transport
GO:0016042 lipid catabolic process
GO:0030308 negative regulation of cell growth
GO:0031579 membrane raft organization
GO:0032429 regulation of phospholipase A2 activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0044257 cellular protein catabolic process
GO:0044265 cellular macromolecule catabolic process
GO:0048260 positive regulation of receptor-mediated endocytosis
GO:0048549 positive regulation of pinocytosis
GO:0051181 cofactor transport
GO:0051186 cofactor metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005794 Golgi apparatus
GO:0008021 synaptic vesicle
GO:0030424 axon
GO:0030425 dendrite
GO:0043025 neuronal cell body
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID MGI:1298204
InterPro IPR002472 Palmitoyl protein thioesterase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF02089
PRINTS PR00414
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1B0P9
UniProt Splice Variant
Entrez Gene 19063
UniGene Mm.452338
RefSeq
MGI ID
MGI Symbol Ppt1
OMIM
CCDS
HPRD
IMGT
EMBL BX545849
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca