Version 5.4
Mus musculus Protein: Slc10a6
Summary
InnateDB Protein IDBP-184886.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc10a6
Protein Name solute carrier family 10 (sodium/bile acid cotransporter family), member 6
Synonyms 8430417G17Rik; C78479; Soat;
Species Mus musculus
Ensembl Protein ENSMUSP00000031263
InnateDB Gene IDBG-184884 (Slc10a6)
Protein Structure
UniProt Annotation
Function Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008508 bile acid:sodium symporter activity
GO:0043250 sodium-dependent organic anion transmembrane transporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0015721 bile acid and bile salt transport
GO:0043251 sodium-dependent organic anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1923000
InterPro IPR002657 Bile acid:sodium symporter
PFAM PF01758
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CXB2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 75750
UniGene
RefSeq NP_083691
MGI ID
MGI Symbol Slc10a6
OMIM
CCDS CCDS19477
HPRD
IMGT
EMBL AJ583504 AK018423 BC127608 BC139343 BC139346
GenPept AAI27609 AAI39344 AAI39347 BAB31203 CAE47479

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca