InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prps2

Summary

InnateDB Protein

IDBP-185556.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prps2

Protein Name

phosphoribosyl pyrophosphate synthetase 2

Synonyms

2610101M19Rik; AA589463; AI464149; Prps-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000026839

InnateDB Gene

IDBG-185554 (Prps2)

Protein Structure

UniProt Annotation

Function

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004749	ribose phosphate diphosphokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016208	AMP binding
GO:0016301	kinase activity
GO:0019003	GDP binding
GO:0030246	carbohydrate binding
GO:0042803	protein homodimerization activity
GO:0043531	ADP binding

Biological Process

GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process
GO:0006167	AMP biosynthetic process
GO:0009116	nucleoside metabolic process
GO:0009165	nucleotide biosynthetic process
GO:0016310	phosphorylation
GO:0019693	ribose phosphate metabolic process
GO:0031100	organ regeneration