InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Grasp

Summary

InnateDB Protein

IDBP-185597.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Grasp

Protein Name

GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

Synonyms

tamalin;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000000543

InnateDB Gene

IDBG-185595 (Grasp)

Protein Structure

UniProt Annotation

Function

Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:10828067}. Cell membrane {ECO:0000269PubMed:10828067}. Note=Primarily localized to the plasma membrane but also distributed diffusely throughout the cytoplasm.

Disease Associations

Tissue Specificity

Highly expressed in brain, heart and lung, and to a lower extent in embryo, kidney and ovary. {ECO:0000269PubMed:10828067, ECO:0000269PubMed:11850456}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030165	PDZ domain binding
GO:0030306	ADP-ribosylation factor binding
GO:0042802	identical protein binding