InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gstm5

Summary

InnateDB Protein

IDBP-185699.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gstm5

Protein Name

glutathione S-transferase, mu 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004134

InnateDB Gene

IDBG-185697 (Gstm5)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0043295	glutathione binding

Biological Process

GO:0006749	glutathione metabolic process
GO:0018916	nitrobenzene metabolic process
GO:0042178	xenobiotic catabolic process
GO:0043627	response to estrogen
GO:0070458	cellular detoxification of nitrogen compound

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0035686	sperm fibrous sheath
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1309466

InterPro

IPR003081 Glutathione S-transferase, Mu class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM