InnateDB Protein
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IDBP-186367.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Serpinb2
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Protein Name
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serine (or cysteine) peptidase inhibitor, clade B, member 2
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Synonyms
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ovalbumin; PAI-2; Planh2;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000065277
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InnateDB Gene
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IDBG-186363 (Serpinb2)
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Protein Structure
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|
Function |
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Not required for normal murine development or survival.
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Subcellular Localization |
Cytoplasm. Secreted, extracellular space.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
0
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
6 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004867
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serine-type endopeptidase inhibitor activity
|
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:97609
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InterPro |
IPR023796
Serpin domain
|
PFAM |
PF00079
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PRINTS |
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PIRSF |
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SMART |
SM00093
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TIGRFAMs |
|
Modification |
|
SwissProt |
P12388
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
Q542A3
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UniProt Splice Variant |
|
Entrez Gene |
18788
|
UniGene |
Mm.405450
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RefSeq |
NP_035241
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MGI ID |
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MGI Symbol |
Serpinb2
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OMIM |
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CCDS |
CCDS15219
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HPRD |
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IMGT |
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EMBL |
AF069683
AF069684
AF069685
AF069686
AF069687
AF069688
AF069689
AF069690
AF069691
AF069692
AF069693
AF069694
AJ000384
AJ000385
AJ000386
AK081487
AK090049
BC138815
BC138817
X16490
|
GenPept |
AAD08915
AAD08916
AAD08917
AAD08918
AAD08919
AAD08920
AAD08921
AAI38816
AAI38818
BAC38231
BAC41065
CAA04047
CAA34507
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