Version 5.4
Mus musculus Protein: Krt71
Summary
InnateDB Protein IDBP-186764.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt71
Protein Name keratin 71
Synonyms AA589543; Ca; Cal4; Cu; Krt2-6g; mK6irs; mK6irs1;
Species Mus musculus
Ensembl Protein ENSMUSP00000023710
InnateDB Gene IDBG-186762 (Krt71)
Protein Structure
UniProt Annotation
Function Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. {ECO:0000269PubMed:14573483}.
Subcellular Localization
Disease Associations
Tissue Specificity Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in Henle and the Huxley layers of the IRS, while expression in the cuticle is unsure (at protein level). {ECO:0000269PubMed:11231308, ECO:0000269PubMed:11703281, ECO:0000269PubMed:14573483}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
GO:0031069 hair follicle morphogenesis
Cellular Component
GO:0005882 intermediate filament
GO:0045095 keratin filament
Protein Structure and Domains
PDB ID MGI:1861586
InterPro IPR001664 Intermediate filament protein
IPR003054 Keratin, type II
IPR009053 Prefoldin
PFAM PF00038
PRINTS PR01276
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9R0H5
PhosphoSite PhosphoSite-Q9R0H5
TrEMBL
UniProt Splice Variant
Entrez Gene 56735
UniGene Mm.358677
RefSeq NP_064340
MGI ID
MGI Symbol Krt71
OMIM
CCDS CCDS27862
HPRD
IMGT
EMBL AB033744 AB100413 AB100414 AB100415 AB100416 AB100417 AB100418 AK004268 AY033497 BC125346 BC125348
GenPept AAI25347 AAI25349 AAK55110 BAA85657 BAB23243 BAC79434 BAC79435 BAC79436 BAC79437 BAC79438 BAC79439

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca