Version 5.4
Mus musculus Protein: Usp43
Summary
InnateDB Protein IDBP-188370.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Usp43
Protein Name ubiquitin specific peptidase 43
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000021288
InnateDB Gene IDBG-188368 (Usp43)
Protein Structure
UniProt Annotation
Function May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2444541
InterPro IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain
PFAM PF00443
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BUM9
PhosphoSite PhosphoSite-Q8BUM9
TrEMBL
UniProt Splice Variant
Entrez Gene 216835
UniGene Mm.481503
RefSeq NP_776115
MGI ID
MGI Symbol Usp43
OMIM
CCDS CCDS24861
HPRD
IMGT
EMBL AK083271 AL732570 BC021474
GenPept AAH21474 BAC38837 CAI52000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca