Version 5.4
Mus musculus Protein: Acrbp
Summary
InnateDB Protein IDBP-188954.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acrbp
Protein Name proacrosin binding protein
Synonyms OY-TES-1; sp32;
Species Mus musculus
Ensembl Protein ENSMUSP00000085632
InnateDB Gene IDBG-188950 (Acrbp)
Protein Structure
UniProt Annotation
Function May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=Colocalizes with proacrosin in the acrosome of sperm. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016504 peptidase activator activity
Biological Process
GO:0007286 spermatid development
GO:0010952 positive regulation of peptidase activity
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005576 extracellular region
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1859515
InterPro IPR009865 Proacrosin binding sp32
PFAM PF07222
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3V140
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 54137
UniGene Mm.347910
RefSeq NP_058541
MGI ID
MGI Symbol Acrbp
OMIM
CCDS CCDS20542
HPRD
IMGT
EMBL AK076691 AK132705 BC011079 D17573 D17574
GenPept AAH11079 BAA04498 BAA04499 BAC36445 BAE21313

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca