Version 5.4
Homo sapiens Protein: GOLGA7
Summary
InnateDB Protein IDBP-18912.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOLGA7
Protein Name golgin A7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000350378
InnateDB Gene IDBG-18910 (GOLGA7)
Protein Structure
UniProt Annotation
Function May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. {ECO:0000269PubMed:14522980, ECO:0000269PubMed:16000296}.
Subcellular Localization Golgi apparatus membrane {ECO:0000269PubMed:14522980, ECO:0000269PubMed:16000296}; Lipid- anchor {ECO:0000269PubMed:14522980, ECO:0000269PubMed:16000296}.
Disease Associations
Tissue Specificity Expressed in all tissues except colon and thymus. {ECO:0000269PubMed:14522980, ECO:0000269PubMed:16000296}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0018230 peptidyl-L-cysteine S-palmitoylation
GO:0043001 Golgi to plasma membrane protein transport
GO:0050821 protein stabilization
Cellular Component
GO:0002178 palmitoyltransferase complex
GO:0005795 Golgi stack
GO:0031228 intrinsic component of Golgi membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR019383 Golgin subfamily A member 7/ERF4
PFAM PF10256
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z5G4
PhosphoSite PhosphoSite-Q7Z5G4
TrEMBL
UniProt Splice Variant
Entrez Gene 51125
UniGene Hs.654773
RefSeq NP_001002296
HUGO HGNC:24876
OMIM 609453
CCDS CCDS34887
HPRD 13595
IMGT
EMBL AB104615 AC009630 AF068291 AF125102 BC012032 CH471080
GenPept AAD39919 AAF65180 AAH12032 BAC82368 EAW63258 EAW63259

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca