InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bysl

Summary

InnateDB Protein

IDBP-189329.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bysl

Protein Name

bystin-like

Synonyms

Bys; Enp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024783

InnateDB Gene

IDBG-189327 (Bysl)

Protein Structure

UniProt Annotation

Function

Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. {ECO:0000269PubMed:17055491, ECO:0000269PubMed:17242206}.

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:17242206}. Nucleus, nucleolus {ECO:0000269PubMed:17242206}. Note=Associated with 40S ribosomal subunits.

Disease Associations

Tissue Specificity

High levels in preimplantation embryos, bone marrow, brain, testis and ovary. {ECO:0000269PubMed:17242206}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001701	in utero embryonic development
GO:0001825	blastocyst formation
GO:0001829	trophectodermal cell differentiation
GO:0007155	cell adhesion
GO:0008283	cell proliferation

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0045177	apical part of cell