Mus musculus Protein: Ubxn4
Summary
InnateDB Protein IDBP-189727.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ubxn4
Protein Name UBX domain protein 4
Synonyms 1300013G12Rik; mKIAA0242; Ubxd2;
Species Mus musculus
Ensembl Protein ENSMUSP00000027592
InnateDB Gene IDBG-189725 (Ubxn4)
Protein Structure
UniProt Annotation
Function Involved in endoplasmic reticulum-associated protein degradation (ERAD). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus envelope {ECO:0000250}. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in many tissues, including brain, heart, kidney, liver, muscle and spleen (at protein level). {ECO:0000269PubMed:16968747}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006986 response to unfolded protein
GO:0008150 biological_process
Cellular Component
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:1915062
InterPro IPR001012 UBX domain
IPR012336 Thioredoxin-like fold
IPR029071 Ubiquitin-related domain
PFAM PF00789
PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF
SMART SM00166
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VCH8
PhosphoSite PhosphoSite-Q8VCH8
TrEMBL Q9CRQ1
UniProt Splice Variant
Entrez Gene 67812
UniGene Mm.473896
RefSeq NP_080666
MGI ID 2DZK
MGI Symbol Ubxn4
OMIM
CCDS CCDS15251
HPRD
IMGT
EMBL AK019371 AK029431 AK075716 AK129098 AK147795 BC019795
GenPept AAH19795 BAB31684 BAC26449 BAC35906 BAC97908 BAE28143