Version 5.4
Mus musculus Protein: Ripply2
Summary
InnateDB Protein IDBP-189822.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ripply2
Protein Name ripply2 homolog (zebrafish)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055369
InnateDB Gene IDBG-189820 (Ripply2)
Protein Structure
UniProt Annotation
Function Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites. {ECO:0000269PubMed:17360776, ECO:0000269PubMed:17531978}.
Subcellular Localization Nucleus {ECO:0000250UniProtKB:Q2WG80}.
Disease Associations
Tissue Specificity Expressed in the embryonic anterior presomitic mesoderm. First expressed in S-I at E8.5, where expression is maintained until E13.5, with an additional stripe of expression sometimes seen in the rostral part of S0 and S-I. {ECO:0000269PubMed:16326386, ECO:0000269PubMed:17531978}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001503 ossification
GO:0001756 somitogenesis
GO:0007219 Notch signaling pathway
GO:0007368 determination of left/right symmetry
GO:0009798 axis specification
GO:0010468 regulation of gene expression
GO:0032525 somite rostral/caudal axis specification
GO:0036342 post-anal tail morphogenesis
GO:0060349 bone morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2685968
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2WG76
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 382089
UniGene
RefSeq NP_001032996
MGI ID
MGI Symbol Ripply2
OMIM
CCDS CCDS40715
HPRD
IMGT
EMBL AB212223 AK081203
GenPept BAC38162 BAE53720

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca