InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Csrp2

Summary

InnateDB Protein

IDBP-189943.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Csrp2

Protein Name

cysteine and glycine-rich protein 2

Synonyms

AW551867; Crp2; SmLim;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020403

InnateDB Gene

IDBG-189941 (Csrp2)

Protein Structure

UniProt Annotation

Function

Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0007275	multicellular organismal development
GO:0030154	cell differentiation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1202907

InterPro

IPR001781 Zinc finger, LIM-type

PFAM

PF00412

PRINTS

PIRSF

SMART

SM00132

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P97314

PhosphoSite

PhosphoSite-P97314

TrEMBL

Q6QMT3

UniProt Splice Variant

Entrez Gene

13008

UniGene

RefSeq

NP_031818

MGI ID

MGI Symbol

Csrp2

OMIM

CCDS

CCDS24165

HPRD

IMGT

EMBL

AK010626 AK012647 AY533303 BC012663 D88792

GenPept

AAH12663 AAS13687 BAA13722 BAB27072 BAB28379