InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Apobec2

Summary

InnateDB Protein

IDBP-190004.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Apobec2

Protein Name

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2

Synonyms

Arp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000047402

InnateDB Gene

IDBG-190002 (Apobec2)

Protein Structure

UniProt Annotation

Function

Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed exclusively in heart and skeletal muscle. {ECO:0000269PubMed:12859895}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008270	zinc ion binding
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines