Mus musculus Protein: Daam2
Summary
InnateDB Protein IDBP-190140.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Daam2
Protein Name dishevelled associated activator of morphogenesis 2
Synonyms 2310016D11Rik; AI843643; AW557870;
Species Mus musculus
Ensembl Protein ENSMUSP00000052085
InnateDB Gene IDBG-190138 (Daam2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity In early embryogenesis, expression is confined to embryonic ectoderm. Highly dynamic expression in later stages of gastrulation. In early somite stages, detected in posterior node and persists until 9-10 somites have developed when expression is concentrated in the chordoneural hinge. During organogenesis, expressed in the CNS, PNS, liver primordia, limb buds and genital tubercle. {ECO:0000269PubMed:15464228, ECO:0000269PubMed:15533824}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005488 binding
GO:0017048 Rho GTPase binding
Biological Process
GO:0007368 determination of left/right symmetry
GO:0016043 cellular component organization
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1923691
InterPro IPR010472 Formin, FH3 domain
IPR010473 Formin, GTPase-binding domain
IPR015425 Formin, FH2 domain
IPR016024 Armadillo-type fold
PFAM PF06367
PF06371
PF02181
PRINTS
PIRSF
SMART SM00498
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80U19
PhosphoSite PhosphoSite-Q80U19
TrEMBL
UniProt Splice Variant
Entrez Gene 76441
UniGene Mm.413411
RefSeq NP_001008232
MGI ID
MGI Symbol Daam2
OMIM
CCDS CCDS37648
HPRD
IMGT
EMBL AC124748 AC165258 AK122266 AY426536 BC050043
GenPept AAH50043 AAR05119 BAC65548