InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ntf3

Summary

InnateDB Protein

IDBP-190190.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ntf3

Protein Name

neurotrophin 3

Synonyms

AI316846; AI835689; Nt3; Ntf-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000052302

InnateDB Gene

IDBG-190188 (Ntf3)

Protein Structure

UniProt Annotation

Function

Seems to promote the survival of visceral and proprioceptive sensory neurons.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Brain and peripheral tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005166	neurotrophin p75 receptor binding
GO:0005515	protein binding
GO:0008083	growth factor activity

Biological Process

GO:0007274	neuromuscular synaptic transmission
GO:0007403	glial cell fate determination
GO:0007411	axon guidance
GO:0007420	brain development
GO:0007422	peripheral nervous system development
GO:0008544	epidermis development
GO:0021675	nerve development
GO:0042490	mechanoreceptor differentiation
GO:0043523	regulation of neuron apoptotic process
GO:0043524	negative regulation of neuron apoptotic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048484	enteric nervous system development
GO:0048666	neuron development
GO:0048699	generation of neurons
GO:0051145	smooth muscle cell differentiation