Version 5.4
Mus musculus Protein: Cntrob
Summary
InnateDB Protein IDBP-190288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cntrob
Protein Name centrobin, centrosomal BRCA2 interacting protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000090651
InnateDB Gene IDBG-190284 (Cntrob)
Protein Structure
UniProt Annotation
Function Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250}. Note=Centriole-associated, asymmetrically localizes to the daughter centriole. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0000910 cytokinesis
GO:0007099 centriole replication
GO:0051299 centrosome separation
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
Protein Structure and Domains
PDB ID MGI:2443290
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CB62
PhosphoSite PhosphoSite-Q8CB62
TrEMBL
UniProt Splice Variant
Entrez Gene 216846
UniGene Mm.473405
RefSeq NP_766148
MGI ID
MGI Symbol Cntrob
OMIM
CCDS CCDS24888
HPRD
IMGT
EMBL AK036710 AL645527 BC058512
GenPept AAH58512 BAC29545 CAQ13013

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca