Version 5.4
Mus musculus Protein: Tmed3
Summary
InnateDB Protein IDBP-190433.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmed3
Protein Name transmembrane emp24 domain containing 3
Synonyms 1200002G13Rik; AW546672; P24b;
Species Mus musculus
Ensembl Protein ENSMUSP00000058723
InnateDB Gene IDBG-190431 (Tmed3)
Protein Structure
UniProt Annotation
Function Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Probably cycles between compartments of the early secretatory pathway. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006810 transport
GO:0008150 biological_process
GO:0015031 protein transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0030126 COPI vesicle coat
GO:0032580 Golgi cisterna membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Protein Structure and Domains
PDB ID MGI:1913361
InterPro IPR009038 GOLD
PFAM PF01105
PF13897
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q78IS1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 66111
UniGene
RefSeq NP_079636
MGI ID
MGI Symbol Tmed3
OMIM
CCDS CCDS23396
HPRD
IMGT
EMBL AK002698 AK004545 BC023338
GenPept AAH23338 BAB22292 BAB23361

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca