Version 5.4
| Mus musculus Protein: Dnahc2 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Protein | IDBP-190821.6 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | Dnahc2 | ||||||||||||
| Protein Name | dynein, axonemal, heavy chain 2 | ||||||||||||
| Synonyms | |||||||||||||
| Species | Mus musculus | ||||||||||||
| Ensembl Protein | ENSMUSP00000047329 | ||||||||||||
| InnateDB Gene | IDBG-190819 (Dnahc2) | ||||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||||
| Function | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). {ECO:0000250}. | ||||||||||||
| Subcellular Localization | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000305}. | ||||||||||||
| Disease Associations | |||||||||||||
| Tissue Specificity | |||||||||||||
| Comments | |||||||||||||
| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||||
| PDB ID | MGI:107731 | ||||||||||||
| InterPro |
IPR003593
AAA+ ATPase domain IPR003959 ATPase, AAA-type, core IPR004273 Dynein heavy chain domain IPR011704 ATPase, dynein-related, AAA domain IPR013594 Dynein heavy chain, domain-1 IPR013602 Dynein heavy chain, domain-2 IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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| PFAM |
PF00004
PF07724 PF13304 PF03028 PF07728 PF08385 PF08393 |
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| PRINTS | |||||||||||||
| PIRSF | |||||||||||||
| SMART |
SM00382
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| TIGRFAMs | |||||||||||||
| Post-translational Modifications | |||||||||||||
| Modification | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | P0C6F1 | ||||||||||||
| PhosphoSite | PhosphoSite-P0C6F1 | ||||||||||||
| TrEMBL | |||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 327954 | ||||||||||||
| UniGene | Mm.247478 | ||||||||||||
| RefSeq | |||||||||||||
| MGI ID | |||||||||||||
| MGI Symbol | Dnah2 | ||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | AK029791 AL596125 AL731687 Z83813 | ||||||||||||
| GenPept | BAC26619 CAB06067 CAI35997 | ||||||||||||