InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Foxm1

Summary

InnateDB Protein

IDBP-191012.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Foxm1

Protein Name

forkhead box M1

Synonyms

AA408308; AW554517; BB238854; Fkh16; Foxm1b; HFH-11B; MPHOSPH2; Mpm2; WIN;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000073041

InnateDB Gene

IDBG-191010 (Foxm1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	35 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008301	DNA binding, bending
GO:0019901	protein kinase binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0000086	G2/M transition of mitotic cell cycle
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001570	vasculogenesis
GO:0001889	liver development
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007389	pattern specification process
GO:0008284	positive regulation of cell proliferation
GO:0009888	tissue development
GO:0032873	negative regulation of stress-activated MAPK cascade
GO:0042127	regulation of cell proliferation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046578	regulation of Ras protein signal transduction
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
GO:0071156	regulation of cell cycle arrest
GO:0090344	negative regulation of cell aging
GO:2000377	regulation of reactive oxygen species metabolic process
GO:2000781	positive regulation of double-strand break repair