InnateDB Protein
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IDBP-191103.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Nrip2
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Protein Name
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nuclear receptor interacting protein 2
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Synonyms
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AW491344; NIX1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000001561
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InnateDB Gene
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IDBG-191101 (Nrip2)
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Protein Structure
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Function |
Down-regulates transcriptional activation by nuclear receptors, such as NR1F2. {ECO:0000269PubMed:10860982}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:10860982}.
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Disease Associations |
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Tissue Specificity |
Expression is restricted to the central nervous system (neurons in the dentate gyrus of the hippocampus, the amygdala, thalamic and hypothalamic regions). {ECO:0000269PubMed:10860982}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1891884
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InterPro |
IPR019103
Aspartic peptidase, DDI1-type
IPR021109
Aspartic peptidase domain
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PFAM |
PF09668
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9JHR9
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PhosphoSite |
PhosphoSite-Q9JHR9
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
60345
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UniGene |
Mm.269883
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RefSeq |
NP_068363
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MGI ID |
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MGI Symbol |
Nrip2
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OMIM |
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CCDS |
CCDS20571
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HPRD |
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IMGT |
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EMBL |
AJ278170
AK134689
AK156526
BC115523
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GenPept |
AAI15524
BAE22242
BAE33744
CAB95737
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