Mus musculus Protein: Fsd1
Summary
InnateDB Protein IDBP-191353.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fsd1
Protein Name fibronectin type 3 and SPRY domain-containing protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000011733
InnateDB Gene IDBG-191351 (Fsd1)
Protein Structure
UniProt Annotation
Function May be involved in microtubule organization and stabilization. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cleavage furrow {ECO:0000250}. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007067 mitotic nuclear division
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005874 microtubule
GO:0032154 cleavage furrow
Protein Structure and Domains
PDB ID MGI:1934858
InterPro IPR001870 B30.2/SPRY domain
IPR003649 B-box, C-terminal
IPR003877 SPla/RYanodine receptor SPRY
IPR003961 Fibronectin, type III
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR018355 SPla/RYanodine receptor subgroup
PFAM PF00622
PF00041
PF01108
PRINTS
PIRSF
SMART SM00502
SM00449
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TPM6
PhosphoSite PhosphoSite-Q7TPM6
TrEMBL
UniProt Splice Variant
Entrez Gene 240121
UniGene Mm.270660
RefSeq NP_899001
MGI ID
MGI Symbol Fsd1
OMIM
CCDS CCDS37661
HPRD
IMGT
EMBL AK140132 AK144257 BC055106
GenPept AAH55106 BAE24249 BAE25801