Version 5.4
Mus musculus Protein: Kpna6
Summary
InnateDB Protein IDBP-191504.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Kpna6
Protein Name karyopherin (importin) alpha 6
Synonyms IPOA7; Kpna5; NPI-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000003828
InnateDB Gene IDBG-191500 (Kpna6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0006606 protein import into nucleus
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060135 maternal process involved in female pregnancy
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1100836
InterPro IPR000225 Armadillo
IPR000357 HEAT
IPR002652 Importin-alpha, importin-beta-binding domain
IPR016024 Armadillo-type fold
PFAM PF00514
PF02985
PF01749
PRINTS
PIRSF
SMART SM00185
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q4FJZ2
UniProt Splice Variant
Entrez Gene 16650
UniGene Mm.418605
RefSeq
MGI ID
MGI Symbol Kpna6
OMIM
CCDS
HPRD
IMGT
EMBL AL671759 CH466552 CT010260
GenPept CAJ18468 EDL30166

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca