Version 5.4
| Mus musculus Protein: Fabp2 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-191911.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Fabp2 | ||||||
| Protein Name | fatty acid binding protein 2, intestinal | ||||||
| Synonyms | Fabpi; I-FABP; | ||||||
| Species | Mus musculus | ||||||
| Ensembl Protein | ENSMUSP00000023820 | ||||||
| InnateDB Gene | IDBG-191909 (Fabp2) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. {ECO:0000269PubMed:11023988}. | ||||||
| Subcellular Localization | Cytoplasm. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Expressed in the small intestine. Highest expression levels in the proximal ileum. {ECO:0000269PubMed:9277406}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | MGI:95478 | ||||||
| InterPro |
IPR000463
Cytosolic fatty-acid binding IPR000566 Lipocalin/cytosolic fatty-acid binding domain IPR011038 Calycin-like |
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| PFAM |
PF00061
PF08212 |
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| PRINTS |
PR00178
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| PIRSF | |||||||
| SMART | |||||||
| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | P55050 | ||||||
| PhosphoSite | PhosphoSite-P55050 | ||||||
| TrEMBL | Q53YP5 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 14079 | ||||||
| UniGene | |||||||
| RefSeq | NP_032006 | ||||||
| MGI ID | |||||||
| MGI Symbol | Fabp2 | ||||||
| OMIM | |||||||
| CCDS | CCDS17813 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AK007995 AY523818 AY523819 BC013457 CH466532 M65034 | ||||||
| GenPept | AAA37589 AAH13457 AAS00549 AAS00550 BAB25397 EDL12315 | ||||||