Version 5.4
Mus musculus Protein: Faim
Summary
InnateDB Protein IDBP-192588.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Faim
Protein Name Fas apoptotic inhibitory molecule
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000035038
InnateDB Gene IDBG-192586 (Faim)
Protein Structure
UniProt Annotation
Function Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. {ECO:0000269PubMed:10075978}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:19168072}.
Disease Associations
Tissue Specificity Widely expressed, with the highest levels in brain, thymus, kidney, and spleen. {ECO:0000269PubMed:10075978}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1344387
InterPro IPR010695 Fas apoptotic inhibitory molecule
PFAM PF06905
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WUD8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 23873
UniGene
RefSeq NP_035940
MGI ID 2KD2
MGI Symbol Faim
OMIM
CCDS CCDS23431
HPRD
IMGT
EMBL AF130367 AK005762 BC079662
GenPept AAD23879 AAH79662 BAB24225

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca