Version 5.4
Mus musculus Protein: Sdc3
Summary
InnateDB Protein IDBP-192890.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sdc3
Protein Name syndecan 3
Synonyms mKIAA0468; syn-3; Synd3;
Species Mus musculus
Ensembl Protein ENSMUSP00000065877
InnateDB Gene IDBG-192888 (Sdc3)
Protein Structure
UniProt Annotation
Function Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism (By similarity). {ECO:0000250}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008092 cytoskeletal protein binding
Biological Process
Cellular Component
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1349163
InterPro IPR003585 Neurexin/syndecan/glycophorin C
IPR027789 Syndecan/Neurexin domain
PFAM PF01034
PRINTS
PIRSF
SMART SM00294
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64519
PhosphoSite PhosphoSite-Q64519
TrEMBL B1ASF6
UniProt Splice Variant
Entrez Gene 20970
UniGene Mm.206536
RefSeq NP_035650
MGI ID
MGI Symbol Sdc3
OMIM
CCDS CCDS38894
HPRD
IMGT
EMBL AK129153 AK150120 AK155127 AL627104 BC054795 BC062093 U52826
GenPept AAB03283 AAH54795 AAH62093 BAC97963 BAE29322 BAE33064

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca