Version 5.4
Mus musculus Protein: Pop5
Summary
InnateDB Protein IDBP-193451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pop5
Protein Name processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000080215
InnateDB Gene IDBG-193449 (Pop5)
Protein Structure
UniProt Annotation
Function Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000171 ribonuclease MRP activity
GO:0004526 ribonuclease P activity
GO:0004540 ribonuclease activity
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0008033 tRNA processing
GO:0016070 RNA metabolic process
GO:0090501 RNA phosphodiester bond hydrolysis
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0000172 ribonuclease MRP complex
GO:0005634 nucleus
GO:0005655 nucleolar ribonuclease P complex
Protein Structure and Domains
PDB ID MGI:2151221
InterPro IPR002759 Ribonuclease P/MRP protein subunit
IPR016819 Ribonuclease P/MRP protein, subunit Pop5
PFAM PF01900
PRINTS
PIRSF PIRSF023803
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DB28
PhosphoSite PhosphoSite-Q9DB28
TrEMBL
UniProt Splice Variant
Entrez Gene 117109
UniGene Mm.24636
RefSeq NP_080674
MGI ID
MGI Symbol Pop5
OMIM
CCDS CCDS19583
HPRD
IMGT
EMBL AK005290 AK012523 AK013257 BC022670
GenPept AAH22670 BAB23935 BAB28294 BAB28751

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca