Version 5.4
Mus musculus Protein: Abhd2
Summary
InnateDB Protein IDBP-193715.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abhd2
Protein Name abhydrolase domain containing 2
Synonyms 2210009N18Rik; Labh-2; LABH2;
Species Mus musculus
Ensembl Protein ENSMUSP00000038361
InnateDB Gene IDBG-193713 (Abhd2)
Protein Structure
UniProt Annotation
Function May play a role in smooth muscle cells migration. {ECO:0000269PubMed:15721306}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart. {ECO:0000269PubMed:11922611, ECO:0000269PubMed:15721306}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0009611 response to wounding
GO:0030336 negative regulation of cell migration
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1914344
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR012020 AB-hydrolase YheT, putative
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PRINTS PR00111
PIRSF PIRSF005211
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QXM0
PhosphoSite PhosphoSite-Q9QXM0
TrEMBL
UniProt Splice Variant
Entrez Gene 54608
UniGene Mm.490505
RefSeq NP_061281
MGI ID
MGI Symbol Abhd2
OMIM
CCDS CCDS21380
HPRD
IMGT
EMBL AF201730 AF546701 AK008690 AK139526 AK153642 BC027098 BC089477
GenPept AAF17566 AAH27098 AAH89477 AAQ12022 BAB25836 BAE24049 BAE32131

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca