InnateDB Protein
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IDBP-19568.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NUP210
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Protein Name
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nucleoporin 210kDa
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Synonyms
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GP210; POM210;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000254508
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InnateDB Gene
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IDBG-19566 (NUP210)
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Protein Structure
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Function |
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. {ECO:0000269PubMed:14517331}.
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Subcellular Localization |
Nucleus, nuclear pore complex {ECO:0000269PubMed:2195063}. Nucleus membrane {ECO:0000269PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269PubMed:2195063}. Endoplasmic reticulum membrane {ECO:0000269PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269PubMed:2195063}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. {ECO:0000269PubMed:10048485}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
16
[view]
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Protein-Protein |
16
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003343
Bacterial Ig-like, group 2
IPR008964
Invasin/intimin cell-adhesion
IPR015919
Cadherin-like
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PFAM |
PF02368
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PRINTS |
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PIRSF |
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SMART |
SM00635
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TIGRFAMs |
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Modification |
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SwissProt |
Q8TEM1
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PhosphoSite |
PhosphoSite-Q8TEM1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23225
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UniGene |
Hs.475525
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RefSeq |
NP_079199
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HUGO |
HGNC:30052
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OMIM |
607703
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CCDS |
CCDS33704
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HPRD |
06368
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IMGT |
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EMBL |
AB020713
AC027124
AC069246
AK026042
AK074101
AK075545
AL117527
BC067089
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GenPept |
AAH67089
BAA74929
BAB15332
BAB84927
BAC11688
CAB55979
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