Version 5.4
Mus musculus Protein: Bank1
Summary
InnateDB Protein IDBP-195711.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bank1
Protein Name B-cell scaffold protein with ankyrin repeats 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000035484
InnateDB Gene IDBG-195709 (Bank1)
Protein Structure
UniProt Annotation
Function Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Specifically expressed in spleen. Highly expressed in immature B-cells and recirculating B-cells, and at low levels in pro-B and pre-B cells. {ECO:0000269PubMed:11782428}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0042113 B cell activation
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2442120
InterPro IPR020683 Ankyrin repeat-containing domain
PFAM PF11929
PF12796
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80VH0
PhosphoSite PhosphoSite-Q80VH0
TrEMBL Q3UFC5
UniProt Splice Variant
Entrez Gene 242248
UniGene Mm.418570
RefSeq NP_001028522
MGI ID
MGI Symbol Bank1
OMIM
CCDS CCDS38645
HPRD
IMGT
EMBL AC101978 AC161171 AC166331 AK041039 AK041242 AK148665 AK156201 AY178734 JF915711
GenPept AAO13613 AEO27499 BAC30794 BAC30875 BAE28636 BAE33622

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca