Version 5.4
Mus musculus Protein: Nmb
Summary
InnateDB Protein IDBP-195744.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nmb
Protein Name neuromedin B
Synonyms 3110023K12Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000026817
InnateDB Gene IDBG-195742 (Nmb)
Protein Structure
UniProt Annotation
Function Stimulates smooth muscle contraction in a manner similar to that of bombesin.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0031710 neuromedin B receptor binding
Biological Process
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0042593 glucose homeostasis
GO:0046887 positive regulation of hormone secretion
GO:0046888 negative regulation of hormone secretion
GO:0050482 arachidonic acid secretion
Cellular Component
GO:0005576 extracellular region
GO:0043005 neuron projection
Protein Structure and Domains
PDB ID MGI:1915289
InterPro IPR000874 Bombesin/neuromedin-B/ranatensin peptide family
PFAM PF02044
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CR53
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 68039
UniGene Mm.22246
RefSeq NP_080799
MGI ID
MGI Symbol Nmb
OMIM
CCDS CCDS21400
HPRD
IMGT
EMBL AK011929 AK014077 BC028490
GenPept AAH28490 BAB27922 BAB29144

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca