InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp2c2

Summary

InnateDB Protein

IDBP-195792.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp2c2

Protein Name

ATPase, Ca++ transporting, type 2C, member 2

Synonyms

1810010G06Rik; mKIAA0703; Spca2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000092794

InnateDB Gene

IDBG-195790 (Atp2c2)

Protein Structure

UniProt Annotation

Function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005388	calcium-transporting ATPase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding

Biological Process

GO:0006812	cation transport
GO:0006816	calcium ion transport
GO:0008152	metabolic process
GO:0070588	calcium ion transmembrane transport

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1916297

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR004014 Cation-transporting P-type ATPase, N-terminal
IPR006068 Cation-transporting P-type ATPase, C-terminal
IPR006413 Calcium-transporting P-type ATPase, subfamily IIA, PMR1-type
IPR008250 P-type ATPase, A domain
IPR023214 HAD-like domain
IPR023299 P-type ATPase, cytoplasmic domain N

PFAM

PF00690
PF00689
PF00122
PF00702
PF08282
PF13419

PRINTS

PR00119
PR00120

PIRSF

SMART

SM00831

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt