InnateDB Protein
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IDBP-195872.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mis12
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Protein Name
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MIS12 homolog (yeast)
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Synonyms
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2510025F08Rik; AU044651; Misc12;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000039500
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InnateDB Gene
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IDBG-195870 (Mis12)
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Protein Structure
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Function |
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. {ECO:0000250}.
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Subcellular Localization |
Nucleus. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Associated with the kinetochore. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated |
Total |
21
[view]
|
Protein-Protein |
21
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
28 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1914389
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InterPro |
IPR008685
Centromere protein Mis12
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PFAM |
PF05859
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9CY25
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PhosphoSite |
PhosphoSite-Q9CY25
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
67139
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UniGene |
Mm.475587
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RefSeq |
NP_080269
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MGI ID |
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MGI Symbol |
Mis12
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OMIM |
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CCDS |
CCDS24973
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HPRD |
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IMGT |
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EMBL |
AK010995
AK132010
AK139957
AK154531
AL596136
BC026790
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GenPept |
AAH26790
BAB27314
BAE20937
BAE24195
BAE32656
CAI26070
CAI26071
CAI26072
CAI26073
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