Mus musculus Protein: Aebp2
Summary
InnateDB Protein IDBP-196122.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aebp2
Protein Name AE binding protein 2
Synonyms AU023766; B230313N05Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000032359
InnateDB Gene IDBG-196120 (Aebp2)
Protein Structure
UniProt Annotation
Function May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3 (By similarity). DNA-binding transcriptional repressor. {ECO:0000250, ECO:0000269PubMed:10329662}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in brain, brown adipose tissue, white adipose tissue, heart, kidney, lung, skeletal muscle, small intestine and spleen. Expressed at low levels in liver. {ECO:0000269PubMed:10329662}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID MGI:1338038
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q9Z248
TrEMBL Z4YJG5
UniProt Splice Variant
Entrez Gene 11569
UniGene Mm.479349
RefSeq NP_848918
MGI ID
MGI Symbol Aebp2
OMIM
CCDS CCDS20674
HPRD
IMGT
EMBL AC133098
GenPept